NF 340 (10 MG)
货号：
3830/10 基本售价：
2964.4 元 规格：
10 mg
产品信息
概述| 货号 | 3830/10 |
| 别名 | 4,4'-(Carbonylbis(imino-3,1-(4-methyl-phenylene)carbonylimino))bis(naphthalene-2,6-disulfonic acid) tetrasodium salt |
性能| 供应商 | Tocris |
| 生物活性 | P2Y11 antagonist; exhibits 520-fold selectivity for P2Y11 over P2Y1, P2Y2, P2Y4, P2Y6 and P2Y12 receptors. Displays competitive antagonism against ATPγS (pIC50 values are 6.43 and 7.14 in Ca2+ and cAMP assays respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >95 % |
| 计算分子量 | 986.84 |
| 分子式 | C37H26N4Na4O15S4 |
| 可溶性/溶解性 | Soluble to 20 mM in water |
| 参考文献 | Meiset al (2010) NF546 [4,4'-(carbonylbis(imino-3,1-phenylene-carbonylimino-3,1-(4-methyl-phenylene)-carbonylimino))-bis(1,3-xylene-γ,γ'-diphosphonic acid) tetrasodium salt] is a non-nucleotide P2Y11 agonist and stimulates release of interleukin-8 from human monocyte-derived dendritic cells. J.Pharmacol.Exp.Ther. 332 238. PMID: 19815812. |
