| 货号 | 2766/10 |
| 别名 | N-[3-[[4-[(3-Aminopropyl)amino]buty |
| 供应商 | Tocris |
| 生物活性 | Selective antagonist of Ca2+-permeable AMPA receptors; blocks AMPA receptors lacking the GluR2 subunit. Protects hippocampal neurons against global ischemia-induced cell death. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >97 % |
| 计算分子量 | 479.91 |
| 分子式 | C22H34N4O.3HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 122306-11-0 |
| 参考文献 | Nilsen and England (2007) A subtype-selective, use-dependent inhibitor of native AMPA receptors. J.Am.Chem.Soc. 129 4902. PMID: 17391037. Nohet al (2005) Blockade of calcium-permeable AMPA receptors protects hippocampal neurons against global ischemia-induced death. Proc.Natl.Acad.Sci.USA 10212230. Koikeet al (1997) Blocking effect of 1-naphthyl acetyl spermine on Ca2+-permeable AMPA receptors in cultured rat hippocampal neurons. Neurosci.Res. 29 27. PMID: 9293490. Tsubokawaet al (1995) Effects of spider toxin and its analogue on glutamate-activated currents in the hippocampal CA1 neuron after ischaemia. J.Neurophysiol. 74 218. PMID: 7472325. |