货号 | 0183/10 |
别名 | L-threo-β-Hydroxyaspartic acid |
供应商 | Tocris |
生物活性 | Potent, competitive, transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor. Also available as part of the Excitatory Amino Acid Transporter Inhibitor Tocriset™. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >97 % |
计算分子量 | 149.1 |
分子式 | C4H7NO5 |
可溶性/溶解性 | Soluble to 100 mM in 1eq. NaOH |
CAS号 | 7298-99-9 |
参考文献 | Nakamuraet al (1993) (2S,3S,4R)-2-(carboxycyclopropyl)glycine, a potent and competitive inhibitor of both glial and neuronal uptake of glutamate. Neuropharmacology 32 833. PMID: 7901789. McBean and Roberts (1985) Neurotoxicity of L-glutamate and DL-threo-3-hydroxyaspartate in the rat striatum. J.Neurochem. 44 247. PMID: 2856883. Johnstonet al (1980) Potentiation of L-glutamate and L-aspartate excitation of cat spinal neurones by the stereoisomers of threo-3-hydroxyaspartate. J.Neurochem. 34 241. PMID: 7452241. |