| 货号 | 3339/1 |
| 别名 | Cocaine and amphetamine-regulated transcript (62-76) (rat, human) |
| 供应商 | Tocris |
| 生物活性 | Cocaine- and amphetamine-regulated transcript (CART) peptide fragment that inhibits food intake. Attenuates NPY-induced feeding and decreases food intake in food-restricted goldfish, and induces anxiogenic-like effects in elevated plus-maze test in rats. Modulates the activity of striatal noradrenergic, and corticostrial and hypothalamic serotoninergic systems, with no major effect on dopaminergic pathways in rat brain. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1570.77 |
| 分子式 | C64H99N17O23S3 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in 20% acetonitrile / water |
| CAS号 | 210978-19-1 |
| 序列号 | YGQVPMCDAGEQCAV |
| 参考文献 | Colomboet al (2003) Effects of ghrelin and other neuropeptides (CART, MCH, orexin A and B, and GLP-1) on release of insulin from isolated rat islets. Pancreas 27 161. PMID: 12883265. Vaarmann and Kask (2001) Cocaine and amphetamine-regulated transcript peptide (CART62-76)-induced changes in regional monoamine levels in rat brain. Neuropeptides 35 292. PMID: 12030814. Volkoff and Peter (2000) Effects of CART peptides on food consumption, feeding and associated behaviors in the goldfish, Carassius auratus: actions on neuropeptide Y- and orexin A-induced feeding. Brain Res. 887 125. PMID: 11134597. |