| 货号 | 3409/10 |
| 别名 | 4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl |
| 供应商 | Tocris |
| 生物活性 | Synthetic retinoid. Retinoic acid receptor β(RARβ) agonist in vivo; RARα and RARγantagonistin vitro. Inhibits breast cell proliferation by inducing active transforming growth factor β(TGFβ) and causes G1arrest. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 380.48 |
| 分子式 | C27H24O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 166977-43-1 |
| 参考文献 | Monteiroet al (2009) Commitment of mouse embryonic stem cells to the adipocyte lineage requires retinoic acid receptor beta and active GSK3. Stem Cells Dev. 18 457. PMID: 18690793. Yanget al (2001) The retinoic acid receptor antagonist, BMS543, inhibits normal breast cell growth by inducing active TGFB and causing cell cycle arrest. Oncogene 20 8025. PMID: 11753686. Chenet al (1995) RAR-specific agonist/antagonists which dissociate transactivation and AP1 transrepression inhibit anchorage-independent cell proliferation. EMBO J. 14 1187. PMID: 7720709. |