货号 | 3904/10 |
别名 | 3-[(-3-Fluorophenyl)sulfonyl]-N,N-d |
供应商 | Tocris |
生物活性 | High affinity, selective 5-HT6 agonist (EC50 = 7.3 nM at the human 5-HT6 receptor). Elevates cortical GABA levels in vivo in rat frontal cortex. Exhibits antidepressant and anxiolytic-like effects. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >99 % |
计算分子量 | 420.33 |
分子式 | C17H18FN3O2< |
可溶性/溶解性 | Soluble to 80 mM in water and to 80 mM in DMSO |
参考文献 | Carret al (2010) Antidepressant and anxiolytic effects of selective 5-HT6 receptor agonists in rats. Psychopharmacol.(Berl.) 213 49. PMID: 20217056. Schechteret al (2008) Neuropharmacological profile of novel and selective 5-HT6 receptor agonists: WAY-181187 and WAY-208466. Neuropsychopharmacol 33 1323. PMID: 17625499. |