| 货号 | 1758/50 |
| 别名 | α-(Trichloromethyl)-4-pyridineethano |
| 供应商 | Tocris |
| 生物活性 | Caspase-3 activator. Acts via inhibition of the oncoprotein ProT, therefore stimulates apoptosome formation and subsequent caspase-3 activation in a cytochrome c-dependent manner. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 240.52 |
| 分子式 | C8H8Cl3NO |
| 可溶性/溶解性 | Soluble to 50 mM in 1eq. HCl |
| CAS号 | 10129-56-3 |
| 参考文献 | Jianget al (2003) Distinctive roles of PHAP proteins and prothymosin-α in a death regulatory pathway. Science 299 223. PMID: 12522243. Nguyen and Wells (2003) Direct activation of the apoptosis machinery as a mechanism to target cancer cells. Proc.Natl.Acad.Sci.U.S.A. 100 7533. PMID: 12808146. |