| 货号 | 5369/1 |
| 供应商 | Tocris |
| 生物活性 | Angiotensin IV analog. Highly potent HGF/c-MET inhibitor (IC50 = 3 pM). Inhibits HGF-induced MDCK cell proliferation and invasion in vitro. Also AT4 receptor antagonist; disrupts LTP stabilization. Antiangiogenic. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 774.95 |
| 分子式 | C41H58N8O7 |
| 可溶性/溶解性 | Soluble to 2 mg/ml in water |
| 序列号 | XYLHPF (Modifications: X = Nle, Leu-3-His-4 peptide bond replaced with CH2NH) |
| 参考文献 | Yamamotoet al (2010) The angiotensin IV analog Nle-Tyr-Leu-psi-(CH2-NH2)3-4-His-Pro-Phe (norleual) can act as a hepatocyte growth factor/c-Met inhibitor. J.Pharmacol.Exp.Ther. 333 161. PMID: 20086056. |