| 货号 | 5017/10 |
| 别名 | 3-[(2S)-2-Azetidinylmethoxy]-pyridi |
| 供应商 | Tocris |
| 生物活性 | High affinity and selective α4β2 nACh receptor agonist (Ki values are 0.05, 148 and 314 nM for α4β2,α7 and α1β1δγ receptors respectively). Stimulates cation efflux in K177 cells expressing α4β2. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 237.13 |
| 分子式 | C9H12N2O.2HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| 参考文献 | Abreoet al (1996) Novel 3-Pyridyl ethers with subnanomolar affinity for central neuronal nicotinic acetylcholine receptors. J.Med.Chem. 39 817. PMID: 8632405. Sullivanet al (1996) A-85380 [3-(2(S)-azetidinylmethoxy) pyridine]: in vitro pharmacological properties of a novel, high affinity α4β2 nicotinic acetylcholine receptor ligand. Neuropharmacology 35 725. PMID: 8887981. |