Ganglioside GM1 Asialo
货号：
15586-1mg 基本售价：
2835.0 元 规格：
1 mg
产品信息
概述| 货号 | 15586-1mg |
| 描述 | Gangliosides are formed from a glycosphingolipid combined with one or more sialic acids at the oligosaccharide chain. They are components of the plasma membrane where they pack densely with cholesterol to form lipid microdomains that modulate signal transduction events. More than 180 gangliosides have been identified and each differ based on the position and number of sialic acid residues. Ganglioside GM1 Asialo is formed by the cleavage of the sialic acid residue from ganglioside GM1 by neuraminidase. It is present in natural killer cells and T cells and, as a component of lipid rafts, it can serve as a glycolipid receptor for bacterial host response signaling.1,2 |
| 别名 | ASGM1;Asialo GM1;Gangliotetraosylceramide; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Moore, M.L.,Chi, M.H.,Goleniewska, K., et al. Differential regulation of GM1 and asialo-GM1 expression by T cells and natural killer (NK) cells in respiratory syncytial virus infection. Viral Immunol. 21(3), 327-339 (2008).
2.McNamara, N.,Khong, A.,McKemy, D., et al. ATP transduces signals from ASGM1, a glycolipid that functions as a bacterial receptor. Proceedings of the National Academy of Sciences of the United States of America 98(16), 9086-9091 (2001).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 1255.6 |
| 分子式 | C62H114N2O23 |
| CAS号 | 71012-19-6 |
| 稳定性 | ≥ 2 years |
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