| 货号 | 1638/10 |
| 别名 | (3β)-3-[2-(Diethylamino)ethoxy]andro |
| 供应商 | Tocris |
| 生物活性 | Inhibitor of cholesterol synthesis and cellular transport, and weak inhibitor of hedgehog (Hh) signaling. Reduces serum sterol levels in rats in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 计算分子量 | 424.07 |
| 分子式 | C25H41NO2.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in water |
| CAS号 | 3039-71-2 |
| 参考文献 | Incardonaet al (2000) Cyclopamine inhibition of sonic hedgehog signal transduction is not mediated through effects on cholesterol transport. Dev.Biol. 224 440. PMID: 10926779. Liscum and Faust (1989) The intracellular transport of low density lipoprotein-derived cholesterol is inhibited in Chinese hamster ovary cells cultured with 3-β-[2-(diethylamino)ethoxy]androst-5-en-17-one. J.Biol.Chem. 264 11796. PMID: 2745416. Cenedellaet al (1980) Concentration-dependent effects of AY-9944 and U18666A on sterol synthesis in brain. Biochem.Pharmacol. 29 2751. PMID: 6159896. |