| 货号 | 4339/1 |
| 供应商 | Tocris |
| 生物活性 | Blocker of Kir1.1 channels; displays >250-fold selectivity for Kir1.1 (Kd values are 1.1, 274 and 361 nM for Kir1.1, Kir3.1/3.2 and Kir3.1/3.4 respectively). Derivative of tertiapin-Q (Cat. No. 1316). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 2428.03 |
| 分子式 | C106H179N33O |
| 可溶性/溶解性 | Soluble to 2 mg/ml in 20% acetonitrile / water |
| 序列号 | ALCNCNRIIIPLQCWKKCGKK (Modifications: Disulfide bridge between 3 - 14, 5 - 18, Lys-21 = C-terminal amide) |
| 参考文献 | Ramuet al (2008) Engineered specific and high-affinity inhibitor for a subtype of inward-rectifier K+ channels. Proc.Natl.Acad.Sci.USA 105 10774. PMID: 18669667. |