| 货号 | 1488/1 |
| 别名 | (trans-Cinnamoyl)-YPGKF-NH2 |
| 供应商 | Tocris |
| 生物活性 | Selective PAR4 antagonist peptide. Inhibits endostatin release and platelet aggregation induced by thrombin. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 739.87 |
| 分子式 | C40H49N7O7 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 327177-34-4 |
| 序列号 | YPGKF (Modifications: Tyr-1 = trans-Cinnamoyl-Tyr, Phe-5 = C-terminal amide) |
| 参考文献 | Hollenberget al (2004) Proteinase-activated receptor-4: evaluation of tethered ligand-derived peptides as probes for receptor function and as inflammatory agonists in vivo. Br.J.Pharmacol. 143 443. PMID: 15451771. Hollenberg and Saifeddine (2001) Proteinase-activated receptor 4 (PAR4): activation and inhibition of rat platelet aggregation by PAR4-derived peptides. Can.J.Physiol.Pharmacol. 79 439. PMID: 11405248. Maet al (2001) Thrombin-induced platelet endostatin release is blocked by a proteinase activated receptor-4 (PAR4) antagonist. Br.J.Pharmacol. 134 701. PMID: 11606309. |