TCS 2312 (1 MG)
货号：
3038/1 基本售价：
2815.7 元 规格：
1 mg
产品信息
概述| 货号 | 3038/1 |
| 别名 | 4'-[5-[[3-[(Cyclopropylamino)methyl]phenyl]amino]-1H-pyrazol-3-yl]-[1,1'-biphenyl]-2,4-diol |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective checkpoint kinase 1 (chk1) inhibitor (Ki = 0.38 nM, EC50 = 60 nM). Enhances the cell killing activity of Gemcitabine (Cat. No. 3259) in breast and prostate cancer cell lines and displays antiproliferative effects in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | -80℃ |
| 纯度 | >97 % |
| 计算分子量 | 412.48 |
| 分子式 | C25H24N4O2.2HCl |
| 可溶性/溶解性 | Soluble to 20 mM in DMSO |
| CAS号 | 838823-32-8 |
| 参考文献 | Tenget al (2007) Structure-based design of (5-arylamino-2H-pyrazol-3-yl)-biphenyl-2',4'-diols as novel and potent human CHK1 inhibitors. J.Med.Chem. 50 5253. PMID: 17887663. |
