| 货号 | 2134/1 |
| 别名 | (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(Ace |
| 供应商 | Tocris |
| 生物活性 | Potent naturally occuring non-nitrogenous κ-opioid selective agonist that displays high affinity at both native (Ki = 4.3 nM) and cloned (Ki = 16 nM) κ-opioid receptors. Also exhibits allosteric modulation of μ-opioid receptor binding. Reported to be brain-penetrant and displays psychoactive properties. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 432.47 |
| 分子式 | C23H28O8 |
| 可溶性/溶解性 | Soluble to 10 mM in ethanol |
| CAS号 | 83729-01-5 |
| 参考文献 | Rothmanet al (2007) Salvinorin A: allosteric interactions at the μ-opioid receptor. J.Pharmacol.Exp.Ther. 320 801. PMID: 17060492. Scheffler and Roth (2003) Salvinorin A: the 'magic mint' hallucinogen finds a molecular target in the kappa opioid receptor. TiPS. 24107. Rothet al (2002) Salvinorin A: a potent naturally occuring nonnitrogenous κ opioid selective agonist. Proc.Natl.Acad.Sci.USA 9911934. |