| 货号 | 2347/10 |
| 别名 | 3-Phenyl-N-[2,2,2-trichloro-1-[[(8- |
| 供应商 | Tocris |
| 生物活性 | Cell-permeable, selective inhibitor of cellular phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α(eIF2α). Protects cells from endoplasmic reticulum stress-induced apoptosis (EC50 ~ 15 μM). |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 479.81 |
| 分子式 | C21H17N4OSCl3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 405060-95-9 |
| 参考文献 | Boyceet al (2005) A selective inhibitor of eIF2α dephosphorylation protects cells from ER stress. Science 307 935. PMID: 15705855. Longet al (2005) Structure-activity relationship studies of salubrinal lead to its active biotinylated derivative. Bioorg.Med.Chem.Lett. 15 3849. PMID: 16002288. |