| 货号 | 3028/560U |
| 别名 | 2-Bromo-3,4-dihydro-3-[3,5-O-[(R)-m |
| 供应商 | Tocris |
| 生物活性 | Competitive, reversible cGMP-dependent protein kinase (PKG) inhibitor; cGMP analog. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >99 % |
| 计算分子量 | 562.27 |
| 分子式 | C18H14BrN5NaO |
| 可溶性/溶解性 | Soluble to 20 mM in water and to 40 mM in DMSO |
| 参考文献 | Valtchevaet al (2008) The commonly used cGMP-dependent protein kinase type I (cGKI) inhibitor Rp-8-Br-PET-cGMPS can activate cGKI in vitro and in intact cells. J.Biol.Chem. 284 556. PMID: 19008225. Qiet al (2007) Protein kinase G regulates the basal tension and plays a major role in nitrovasodilator-induced relaxation of porcine coronary veins. Br.J.Pharmacol. 152 1060. PMID: 17891157. Weiet al (1996) Identification of competitive antagonists of the rod photoreceptor cGMP-gated cation channel: beta-phenyl-1,N2-etheno-substituted cGMP analogues as probes of the cGMP-binding site. Biochemistry 35 16815. PMID: 8988020. |