货号 | 2794/10 |
别名 | 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidi |
供应商 | Tocris |
生物活性 | Negative control for the Src kinase inhibitor PP 2 (Cat. No. 1407). Inhibits EGFR kinase (IC50 = 2.7 μM). |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 211.22 |
分子式 | C11H9N5 |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
CAS号 | 5334-30-5 |
参考文献 | Houet al (2007) PP2, a potent inhibitor of Src family kinases, protects against hippocampal CA1 pyramidal cell death after transient global brain ischemia. Neurosci.Letts. 420235. Traxleret al (1997) Use of a pharmacophore model for the design of EGF-R tyrosine kinase inhibitors: 4-(phenylamino)pyrazolo[3,4-d]pyrimidines. J.Med.Chem. 40 3601. PMID: 9357527. |