货号 | 3399/1 |
供应商 | Tocris |
生物活性 | Encephalitogenic peptide that induces T cell proliferation with Th1 polarization in the CNS. Major antigenic component implicated in the pathophysiology of multiple sclerosis. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 1555.8 |
分子式 | C74H114N20O17 |
可溶性/溶解性 | Soluble to 2 mg/ml in water |
CAS号 | 118506-26-6 |
序列号 | VHFFKNIVTPRTP |
参考文献 | Deraoset al (2008) Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP87-99) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: Implications in triggering disease. J.Med.Chem. 51 7834. PMID: 19053745. Hofstetteret al (2005) Does the frequency and avidity spectrum of the neuroantigen-specific T cells in the blood mirror the autoimmune process in the central nervous system of mice undergoing experimental allergic encephalomyelitis? J.Immunol. 224598. Joneset al (1992) The synthetic 87-99 peptide of myelin basic protein is encelphalitogenic in Buffalo rats. J.Neuroimmunol. 37 203. PMID: 1373154. |