| 货号 | 1217/5 |
| 别名 | N-[9-Chloro-2-(2-furanyl)[1,2,4]-tr |
| 供应商 | Tocris |
| 生物活性 | A potent and highly selective antagonist at the human A3 adenosine receptor (Ki values are 0.65, 305, and 52 nM at hA3, rA1 and rA2A respectively. Displays an IC50 value > 1 μM for inhibition of binding to rat A3receptors). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 403.83 |
| 分子式 | C21HClN5O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO with gentle warming |
| CAS号 | 183721-15-5 |
| 参考文献 | Kimet al (1998) Derivatives of the triazoloquinazoline adenosine antagonist (CGS 15943) having high potency at the human A2B and A3 receptor subtypes. J.Med.Chem. 41 2835. PMID: 9667972. Jacobsonet al (1997) Pharmacological characterization of novel A3 adenosine receptor selective antagonists. Neuropharmacology 36 1157. PMID: 9364471. Kimet al (1996) Derivatives of the triazoloquinazoline adenosine antagonist (CGS 15943) are selective for the human A3 receptor subtype. J.Med.Chem. 39 4142. PMID: 8863790. |