| 货号 | 2748/10 |
| 别名 | 3-[7-(2,4-Dimethoxyphenyl)-2,3,6,7- |
| 供应商 | Tocris |
| 生物活性 | Selective inhibitor of P-selectin-mediated cell adhesion (IC50 = 1.97 μM) that displays no effects on L-selectin- and E-selectin-mediated adhesion. Blocks P-selectin-mediated binding in vitro and leukocyte accumulation in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >97 % |
| 计算分子量 | 375.44 |
| 分子式 | C19H21NO5S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 257292-29-8 |
| 参考文献 | Kailaet al (2007) Synthesis and biological evaluation of quinoline salicylic acids as P-selectin antagonists. J.Med.Chem. 50 21. PMID: 17201408. Ohtaet al (2001) Inhibition of P-selectin specific cell adhesion by a low molecular weight, non-carbohydrate compound, KF38779. Inflamm.Res. 50 544. PMID: 11766994. Haggertyet al (2000) Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small moleculaes that perturb mitosis. Chem.Biol. 7 275. PMID: 10780927. |