| 货号 | 1196/500U |
| 供应商 | Tocris |
| 生物活性 | Highly selective ETB endothelin receptor agonist (Ki values are 0.016 and 1900 nM at ETB and ETA receptors respectively). Discriminates two subpopulations of ETBreceptors. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1820 |
| 分子式 | C86H117N17O2 |
| 可溶性/溶解性 | Soluble to 0.70 mg/ml in water |
| 序列号 | DEEAVYFAHLDIIW (Modifications: Asp-1 = Suc-Asp) |
| 参考文献 | Mazzoniet al (1999) Suc-[Glu9, Ala11,15]-endothelin-1 (8-21), IRL 1620, identifies two populations of ETB receptors in guinea-pig bronchus. Br.J.Pharmacol. 127 1406. PMID: 10455290. Hayneset al (1993) Endothelin; progress in pharmacology and physiology. TiPS 14 225. PMID: 8372400. Sakamotoet al (1993) Distinct subdomains of human endothelin receptors determine their selectivity to endothelinA-selective antagonist and endothelinB-selective agonists. J.Biol.Chem. 268 8547. PMID: 8473300. Takaiet al (1992) A potent and specific agonist, Suc-[Glu9,Ala11,15]-endothelin-1(8-21), IRL 1620, for the ETB receptor. Biochem.Biophys.Res.Commun. 184 953. PMID: 1315540. |