| 货号 | 3260/10 |
| 别名 | (8S,10S)-10-[(3-Amino-2,3,6-trideox |
| 供应商 | Tocris |
| 生物活性 | Antibiotic antitumor agent. Inhibits the synthesis and function of DNA (IC50 = 62.7 μM in rat glioblastoma cell lines) and inhibits the relaxing property of topoisomerase II. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >97 % |
| 计算分子量 | 579.98 |
| 分子式 | C27H29NO11.HCl |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
| CAS号 | 56390-09-1 |
| 参考文献 | Schott and Robert (1989) Comparative activity of anthracycline 13-dihydrometabolites against rat glioblastoma cells in culture. Biochem.Pharmacol. 38 4069. PMID: 2597184. Cersosimoet al (1986) Epirubicin: a review of pharmacology, clinical activity, and adverse effects of an adriamycin analogue. J.Clin.Oncol. 4 425. PMID: 3005521. Spadariet al (1986) DNA polymerases and DNA topoisomerases as targets for the development of anticancer drugs. Anticancer Res. 6 935. PMID: 3026237. |