| 货号 | 4160/1 |
| 别名 | (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[( |
| 供应商 | Tocris |
| 生物活性 | Non-calcemic vitamin D3 (Cat. No. 4156) analog and VDR ligand. Suppresses parathyroid hormone (PTH) mRNA expression in vitroandin vivo. Exhibits similar effects to calcitriol (Cat. No. 2551) in osteoblast-like cells. Inhibits tumor growth of osteosarcoma in vitro in combination with all-trans retinoic acid. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >95 % |
| 计算分子量 | 418.61 |
| 分子式 | C26H42O4 |
| 可溶性/溶解性 | Soluble in DMSO and in ethanol |
| 参考文献 | Barrogaet al (2000) Inhibitory effects of 22-oxa-calcitriol and all-trans retinoic acid on the growth of a canine osteosarcoma derived cell-line in vivo and its pulmonary metastasis in vivo. Res.Vet.Sci. 68 79. PMID: 10684763. Monier-Faugereet al (1999) 22-Oxacalcitriol suppresses secondary hyperparathyroidism without inducing low bone turnover in dogs with renal failure. Kidney Int. 55 821. PMID: 10027919. |