货号 | 1160/100U |
别名 | ET-1 |
供应商 | Tocris |
生物活性 | Endogenous potent vasoconstrictor peptide that is an agonist at ETA and ETB receptors. Modulates vascular tone. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 2492 |
分子式 | C109H159O32N |
可溶性/溶解性 | Soluble to 1 mg/ml in water |
序列号 | CSCSSLMDKECVYFCHLDIIW (Modifications: Disulfide bridge between 1 - 15, 3 - 11) |
参考文献 | Servitjaet al (1998) Involvement of ETA and ETB receptors in the activation of phospholipase D by endothelins in cultured rat cortical astrocytes. Br.J.Pharmacol. 124 1728. PMID: 9756390. Inoueet al (1989) The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc.Natl.Acad.Sci.U.S.A. 86 2863. PMID: 2649896. Yanagisawa and Masaski (1989) Molecular biology and biochemistry of the endothelins. TiPS 10 374. PMID: 2690429. Yanagisawaet al (1988) Primary structure, synthesis, and biological activity of rat endothelin, and endothelium-derived vasoconstrictor peptide. Proc.Natl.Acad.Sci.U.S.A. 85 6964. PMID: 3045827. |