GSK-J4 (Free base)
货号:
2762-5 基本售价:
2735.0 元 规格:
5mg
产品信息
概述货号 | 2762-5 |
描述 | GSK- J4 is cell-permeable ethyl ester of GSK-J1 (Cat. Nos. 2260 & 2761). Acts as a histone demethylase JMJD3/UTX inhibitor. Inhibits demethylation of histone H3K27. Reduces LPS-induced proinflammatory cytokine production in primary human macrophages (IC₅₀ = 9 μM for the inhibition of TNFα release). Rescues newborn pups from embryonic lethality in BRAF knockin mice which recapitulate major features of RASopathies. |
性能供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | -20℃ |
外观 | Yellow waxy solid |