| 货号 | 4618/10 |
| 别名 | N-((2S)-2-(((1Z)-1-Methyl-3-oxo-3-( |
| 供应商 | Tocris |
| 生物活性 | PPARα antagonist (IC50 = 0.24 μM). Enhances the binding affinity of the PPARα ligand-binding domain to the co-repressor proteins SMRT and NCoR. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 619.67 |
| 分子式 | C35H36F3N3 |
| 可溶性/溶解性 | Soluble to 75 mM in DMSO and to 20 mM in ethanol |
| 参考文献 | Mulleret al (2009) An innovative method to study target protein-drug interactions by mass spectrometry. J.Med.Chem. 52 2875. PMID: 19379014. Xuet al (2002) Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα. Nature 415 813. PMID: 11845213. |