| 货号 | 3375/1 |
| 别名 | N,N-Dimethyl-L-valyl-N-[(1S,2R)-2-m |
| 供应商 | Tocris |
| 生物活性 | Tubulin polymerization inhibitor. Noncompetitively inhibits binding of radiolabeled vincristine to tubulin (Ki = 1.4 μM) and induces tubulin aggregation in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >95 % |
| 计算分子量 | 899.11 |
| 分子式 | C42H68N6O6 |
| 可溶性/溶解性 | Soluble in DMSO |
| 参考文献 | Baiet al (1995) Interaction of dolastatin 10 with tubulin: induction of aggregation and binding and dissociation reactions. Mol.Pharmacol. 47 965. PMID: 7746283. Baiet al (1990) Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites. J.Biol.Chem. 265 17141. PMID: 2211617. |