| 货号 | 9002845-1mg |
| 描述 | Estriol-d2 is intended for use as an internal standard for the quantification of estriol (Item Nos. ISO60164|10006484) by GC- or LC-MS. Estriol is a metabolite of estradiol (Item Nos. ISO60155|10006315) and a major estrogen produced in the later stages of pregnancy. In a longitudinal study in healthy pregnant women, total plasma estriol levels increased from <10 ng/ml at 8-10 weeks gestation to approximately 150 ng/ml at week 38.1 The majority of the estriol synthesized in the later stages of pregnancy originates from fetal dehydroepiandrosterone sulfate (DHEAS; Item No. 15873) and serves as a direct marker of fetal adrenal gland activity.2 Saliva contains primarily unbound and unconjugated estriol and is commonly used for monitoring estriol levels.2,3 Plasma levels of estriol in males and non-pregnant females is less than 2 ng/ml.4 |
| 别名 | E3-d2;16α-hydroxy-17β-Estradiol-d2;1,3,5(10)-Estratriene-3,16α,17β-triol-d2; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Peter, M.,Dörr, H.G., and Sippell, W.G. Changes in the concentrations of dehydroepiandrosterone sulfate and estriol in maternal plasma during pregnancy: A longitudinal study in healthy women throughout gestation and at term. Hormone Research 42, 278-281 (1994). 2.Goodwin, T.M. A role for estriol in human labor, term and preterm. American Journal of Obstetics and Gynecology 180, S208-S213 (1999). 3.Voss, H.F. Hormonal pathways of preterm birth. American Journal of Obstetics and Gynecology 180, S226-S231 (1999). 4.. Steroid levels in humans. (1999). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 290.4 |
| 分子式 | C18H22D2O3 |
| CAS号 | 53866-32-3 |
| 稳定性 | ≥ 2 years |
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