Quin-2 AM
货号：
20422-1mg 基本售价：
2646.0 元 规格：
1 mg
产品信息
概述| 货号 | 20422-1mg |
| 描述 | Quin-2 AM is a cell-permeant acetoxymethyl ester of the high-affinity fluorescent calcium indicator quin-2 (Item No. 20421). As quin-2 AM enters cells, it is hydrolyzed by intracellular esterases to produce quin-2. Quin-2 binds calcium with a Kd value of 115 nM.1 It displays high selectivity for calcium, as it is not affected by sodium gradients, membrane potential, or intracellular pH.1 High affinity probes like quin-2 are ideal for monitoring low levels of calcium, as are found in resting cells.1,2 Loadings of up to 2 mM quin-2 are without serious toxic effects, so quin-2 may be used to buffer intracellular calcium transients. Excitation and emission maxima for quin-2 are 339 and 492 nm, respectively. |
| 别名 | Quin-2 Acetoxymethyl ester; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Tsien, R.Y.,Pozzan, T. and Rink.T.J. Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator. J.Cell.Biol. 947(2), 325-334 (1982).
2.Minta, A.,Kao, J.P. and Tsien, R.Y. Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores. The Journal of Biological Chemisty 264(14), 8171-8178 (1989).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥90% |
| 计算分子量 | 829.8 |
| 分子式 | C38H43N3O18 |
| CAS号 | 83104-85-2 |
| 稳定性 | ≥ 2 years |
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