货号 | 1868/10 |
别名 | Bis[amino(methylthio)methylene]buta |
供应商 | Tocris |
生物活性 | Inactive analog of U0126 (Cat. No. 1144). Used as a negative control. Does not inhibit MEK at concentrations up to 100 μM. |
运输条件 | Blue Ice |
存放说明 | Ambient |
计算分子量 | 226.31 |
分子式 | C8H10N4S2 |
可溶性/溶解性 | Soluble to 100 mM in DMSO |
CAS号 | 108923-79-1 |
参考文献 | Sekaret al (2001) Concerted transcriptional activation of the low density lipoprotein receptor gene by insulin and luteinizing hormone in cultured porcine granulosa-luteal cells: possible convergence of protein kinase A, phosphatidylinositol 3-kinase, and mitogen-activated protein kinase signaling pathways. Endocrinology 142 2921. PMID: 11416012. Fitzgerald (2000) Regulation of voltage-dependent calcium channels in rat sensory neurones involves a Ras-mitogen-activated protein kinase pathway. J.Physiol. 527 433. PMID: 10990531. Favataet al (1998) Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J.Biol.Chem. 273 18623. PMID: 9660836. |