| 货号 | 1147/10 |
| 别名 | 2-Amino-(N,N)-1-bis(hexadecahydro-6 |
| 供应商 | Tocris |
| 生物活性 | Anti-neoplastic antibiotic. Inhibits RNA polymerase and is a potent inducer of apoptosis. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 1255.43 |
| 分子式 | C22H26N2O3.HCl |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO |
| CAS号 | 130495-35-1 |
| 参考文献 | Jeeningaet al (1998) The mechanism of actinomycin D-mediated inhibition of HIV-1 reverse transcription. Nucleic Acids Res. 26 5472. PMID: 9826774. Glynnet al (1992) Apoptosis induced by actinomycin D, camptothecin or aphidicolin can occur in all phases of the cell cycle. Biochem.Soc.Trans. 20 84S. PMID: 1634006. Aktipiset al (1981) A kinetic study on the mechanism of inhibition of RNA synthesis catalyzed by DNA-dependent RNA polymerase. Differences in inhibition by ethidium bromide, 3,8-diamino-6-ethylphenanthridinium bromide and actinomycin D. Biochim.Biophys.Acta 655 278. PMID: 7025910. |