ProINDY (10 MG)
货号：
4998/10 基本售价：
2607.5 元 规格：
10 mg
产品信息
概述| 货号 | 4998/10 |
| 别名 | (1Z)-1-(5-Acetyloxy3-ethyl-2(3H)-benzothiazolylidene)-2-propanone |
性能| 供应商 | Tocris |
| 生物活性 | DYRK1A/B inhibitor; prodrug form of INDY (Cat. No. 4997). Cell permeable. Inhibits phosphorylation of tau protein and rescues repressed calcineurin/NFAT signaling. Recovers Xenopus embryos from head malformation induced by DYRK1A overexpression in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 277.34 |
| 分子式 | C14H15NO3S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Ogawaet al (2010) Development of a novel selective inhibitor of the Down syndrome-related kinase Dyrk1A. Nat.Commun. 1 86. PMID: 20981014. |
