| 货号 | 4422/1 |
| 供应商 | Tocris |
| 生物活性 | N-terminally acylated analog of LF 11 (Cat. No. 4421). Displays enhanced antibacterial and LPS-binding activities. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1712.11 |
| 分子式 | C81H134N26O1 |
| 可溶性/溶解性 | Soluble to 2 mg/ml in 30% acetonitrile / water |
| 序列号 | FQWQRNIRKVR (Modifications: Phe-1 = CH3-(CH2)10-CO-NH-Phe, Arg-11 = C-terminal amide) |
| 参考文献 | Rosenfeldet al (2010) Effect of the hydrophobicity to net positive charge ratio on antibacterial and anti-endotoxin activities of structurally similar antimicrobial peptides. Biochemistry 49 853. PMID: 20058937. Zweyticket al (2006) Influence of N-acylation of a peptide derived from human lactoferricin on membrane selectivity. Biochim.Biophys.Acta 1758 1426. PMID: 16616888. Andraet al (2005) Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide. Biochem.J. 385 135. PMID: 15344905. |