货号 | 2576/1 |
供应商 | Tocris |
生物活性 | Endogenous substance P homolog that is a selective agonist at the tachykinin NK1 receptor (IC50 values are 1.8, 370 and 480 nM for NK1, NK3 and NK2 receptors respectively). Has proliferative and antiapoptotic actions on B-cells in vitro and is antihypertensive in vivo. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 1185.4 |
分子式 | C54H84N14O14S |
可溶性/溶解性 | Soluble to 0.70 mg/ml in water |
CAS号 | 491851-53-7 |
序列号 | TGKASQFFGLM (Modifications: Met- 11= C-terminal amide) |
参考文献 | Bellucciet al (2002) Pharmacological profile of the novel mammalian tachykinin hemokinin 1. Br.J.Pharmacol. 135 266. PMID: 11786503. Kurtzet al (2002) Identification, localization and receptor characterization of novel mammalian substance P-like peptides. Gene 296 205. PMID: 12383518. Zhanget al (2000) Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis. Nature Immunol. 1392. |