| 货号 | 4984/10 |
| 别名 | 2-(3-Bromophenyl)-3-(2,4-dimethoxyp |
| 供应商 | Tocris |
| 生物活性 | Inhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex. Inhibits actin polymerization (IC50= 11 μM). Does not inhibit budding or fission yeast Arp2/3 complexes. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 394.28 |
| 分子式 | C17H16BrNO3S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Hetricket al (2013) Small molecules CK-666 and CK-869 inhibit actin-related protein 2/3 complex by blocking an activating conformational change. Chem Biol. 20 701. PMID: 23623350. Nolenet al (2009) Characterization of two classes of small molecule inhibitors of Arp2/3 complex. Nature 460 1031. PMID: 19648907. |