货号 | 1785/1 |
供应商 | Tocris |
生物活性 | Cell-permeable synthetic peptide inhibitor of Bax conformational change and mitochondrial translocation. Designed based on the Bax-binding domain of human Ku70. Inhibits Bax-mediated apoptosis in vitro. Shown to inhibit anti-cancer drug-induced apoptosis in vitro. Negative control (Cat. No. 1787) available. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 586.79 |
分子式 | C27H50N6O6S |
可溶性/溶解性 | Soluble to 1 mg/ml in water |
序列号 | VPMLK |
参考文献 | Sawatzkyet al (2006) The involvement of the apoptosis-modulating proteins ERK 1/2, Bcl-xL and Bax in the resolution of acute inflammation in vivo. Am.J.Pathol. 168 33. PMID: 16400007. Yoshidaet al (2004) Bax-inhibiting peptide derived from mouse and rat Ku70. Biochem.Biophys.Res.Commun. 321 961. PMID: 15358121. |