| 货号 | 2420/1 |
| 别名 | [pGlu1]-Apelin-13 |
| 供应商 | Tocris |
| 生物活性 | Highly potent pyroglutamyl form of apelin-13. Endogenous ligand for apelin APJ receptor (EC50 = 0.37 nM) that displays potent vascular effects in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1533.81 |
| 分子式 | C69H108N22O16S |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 217082-60-5 |
| 序列号 | XRPRLSHKGPMPF (Modifications: X = Glp) |
| 参考文献 | Kagiyamaet al (2005) Central and peripheral cardiovascular actions of apelin in conscious rats. Regul.Pept. 125 55. PMID: 15582714. Kleinzet al (2005) Emerging roles of apelin in biology and medicine. Pharmacol.Ther. 107 198. PMID: 15907343. Katugampolaet al (2001) [125I]-(Pyr1)Apelin-13 is a novel radioligand for localizing the APJ orphan receptor in human and rat tissues with evidence for a vasoconstrictor role in man. Br.J.Pharmacol. 132 1255. PMID: 11250876. Tatemotoet al (1998) Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochem.Biophys.Res.Comm. 251471. |