货号 | 1168/200U |
别名 | [Leu31 , Pro34]-NPY (porcine) |
供应商 | Tocris |
生物活性 | High affinity neuropeptide Y Y1 receptor agonist (Ki = 0.54 nM). Also shows affinity for Y5receptors. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 4223 |
分子式 | C190H286N54O |
可溶性/溶解性 | Soluble to 1 mg/ml in 0.25% acetic acid |
序列号 | YPSKPDNPGEDAPAEDLARYYSALRHYINL (Modifications: Tyr-36 = C-terminal amide) |
参考文献 | Kasket al (1998) Evidence for involvement of neuropeptide Y receptors in the regulation of food intake: studies with Y1-selective antagonist BIBP3226. Br.J.Pharmacol. 124 1507. PMID: 9723965. Michelet al (1998) XVI.International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors. Pharmacol.Rev. 50 143. PMID: 9549761. Bardet al (1995) Cloning and functional expression of a human Y4 subtype receptor for pancreatic polypeptide, neuropeptide Y, and peptide YY. J.Biol.Chem. 270 26762. PMID: 7592911. Fuhlendorffet al (1990) [Leu31, Pro34]Neuropeptide Y: a specific Y1 receptor agonist. Proc.Natl.Acad.Sci.U.S.A. 87 182. PMID: 2153286. |