| 货号 | 17602-500mg |
| 描述 | O-Phospho-D-serine is a phosphorylated form of D-serine, a natural amino acid made from L-serine by serine racemase in the mammalian central nervous system.1 It can be dephosphorylated by phosphoserine phosphatase, like its isomer O-phospho-L-serine (L-SOP; Item No. 16151).2 Unlike L-SOP, O-phospho-D-serine is a weak agonist of the metabotropic glutamate receptor mGluR4 (IC50 = 1,260 µM vs. 4 µM for L-SOP) and poorly blocks phosphatidylserine receptor-mediated phagocytosis.3,4 |
| 别名 | D-O-Phosphoserine;D-Serine-O-Phosphate;D-SOP; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Xia, M.,Liu, Y.,Figueroa, D.J., et al. Characterization and localization of a human serine racemase. Brain Res.Mol.Brain Res. 125, 96-104 (2004). 2.Moro-Furlani, A.M.,Turner, V.S., and Hopkinson, D.A. Genetical and biochemical studies on human phosphoserine phosphatase. Ann.Hum.Genet. 43, 323-333 (1980). 3.Thomsen, C., and Suzdak, P.D. Serine-O-phosphate has affinity for type IV, but not type I, metabotropic glutamate receptor. NeuroReport 4, 1099-1101 (1993). 4.Boettner, D.R.,Huston, C.D.,Sullivan, J.A., et al. Entamoeba histolytica and Entamoeba dispar utilize externalized phosphatidylserine for recognition and phagocytosis of erythrocytes. Infection and Immunity 73(6), 3422-3430 (2005). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 185.1 |
| 分子式 | C3H8NO6P |
| CAS号 | 73913-63-0 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |