Smo Antagonist, SA1
货号：
2154-5 基本售价：
2540.0 元 规格：
5mg
产品信息
概述| 货号 | 2154-5 |
| 描述 | A Smoothened (Smo) antagonist. SA1 inhibits Hh pathway by interacting directly with Smo. Inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC₅₀ = 3.1 µM). Also inhibits the localization of Smo to cilia. Treatment of Ptch1-/- MEFs with SA1 suppresses the β-galactosidase activity (IC₅₀ = 3.8 µM) and inhibits the expression of Gli1 and Ptch1 in ASZ1 cells. |
性能| 供应商 | Biovision |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 外观 | Crystalline solid |
