| 货号 | 2011/10 |
| 别名 | (R)-N-Methyl-γ-(2-methylphenoxy)-ben |
| 供应商 | Tocris |
| 生物活性 | Potent and selective noradrenalin re-uptake inhibitor (Ki values are 5, 77 and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively). Displays minimal affinity for a range of other neurotransmitter receptors and transporters (Ki > 1 μM). Antidepressant. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 291.82 |
| 分子式 | C17H21NO.HCl |
| 可溶性/溶解性 | Soluble to 50 mM in water with gentle warming |
| CAS号 | 82248-59-7 |
| 参考文献 | Bymasteret al (2002) Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder. Neuropsychopharmacology 27 699. PMID: 12431845. Wonget al (1982) A new inhibitor of norepinephrine uptake devoid of affinity for receptors in rat brain. J.Pharmacol.Exp.Ther. 222 61. PMID: 6123593. |