| 货号 | 2200/10 |
| 别名 | 6-[[2-(1-Methylethyl)phenyl]]sulfon |
| 供应商 | Tocris |
| 生物活性 | Potent, selective non-peptidic neuropeptide Y1 receptor antagonist (Ki = 48 nM); selective over Y2 and Y5 receptors (Ki > 10 μM). Antagonizes NPY-mediated inhibition of cAMP accumulation in SK-N-MC cells (IC50 = 8.2 nM). |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 371.41 |
| 分子式 | C18H17N3O4S |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 181468-88-2 |
| 参考文献 | Wielgosz-Collinet al (2002) 8-Amino-5-nitro-6-phenoxyquinolines:potential non-peptidic neuropeptide Y receptor ligands. J.Enz.Inhib.Med.Chem. 17449. Wrightet al (1996) 8-Amino-6-(arylsulphonyl)-5-nitroquinolines: novel nonpeptide neuropeptide Y1 receptor antagonists. Bioorg.Med.Chem.Lett. 61809. |