货号 | 3747/10 |
别名 | 2-Methylpropanethioic acid S-[7-oxo-7-[(4-phenyl-2-thiazolyl)a |
供应商 | Tocris |
生物活性 | Histone deacetylase (HDAC) inhibitor. Inhibits growth of various cancer cells in vitro(EC50 = 1.1 - 9.1 μM). |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 390.56 |
分子式 | C20H26N2O2S2 |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
CAS号 | 848354-66-5 |
参考文献 | Sandaet al (2007) Proteome analyses of the growth inhibitory effects of NCH-51, a novel histone deacetylase inhibitor, on lymphoid malignant cells. Leukemia 21 2344. PMID: 17690692. Suzukiet al (2005) Novel inhibitors of human histone deacetylases: design, synthesis, enzyme inhibition, and cancer cell growth inhibition of SAHA-based non-hydroxamates. J.Med.Chem. 48 1019. PMID: 15715470. |