货号 | 19660-5mg |
描述 | LPS from Escherichia coli O55:B5 is a form of lipopolysaccharide (LPS) extracted from wild-type S-form E. coli serotype O55:B5. It is commonly used to activate toll-like receptor 4 (TLR4) on leukocytes, eliciting inflammatory signaling in isolated cells and in vivo.1,2,3,4 This form of LPS includes three regions, the O-antigenic polysaccharide chain, the core oligosaccharide, and lipid A. |
供应商 | Cayman |
应用文献 | |
1.Brauer, R.B.,Gegenfurtner, C.,Neumann, B., et al. Endotoxin-induced lung inflammation is independent of the complement membrane attack complex. Infection and Immunity 68(3), 1626-1632 (2000). 2.Jungi, T.W.,Sager, H.,Adler, H., et al. Serum factors, cell membrane CD14, and β2 integrins are not required for activation of bovine macrophages by lipopolysaccharide. Infection and Immunity 65(9), 3577-3584 (1997). 3.Li, C.C.,Munitic, I.,Mittelstadt, P.R., et al. Suppression of dendritic cell-derived IL-12 by endogenous glucocorticoids is protective in LPS-induced sepsis. PLOS Biology 13(10), (2015). 4.Migale, R.,Herbert, B.R.,Lee, Y.S., et al. Specific lipopolysaccharide serotypes induce differential maternal and neonatal inflammatory responses in a murine model of preterm labor. American Journal of Pathology 185(9), 2390-2401 (2015). | |
运输条件 | Wet ice in continental US; may vary elsewhere |
存放说明 | 2-8 |
稳定性 | ≥ 2 years |
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