TASIN-1
货号：
21155-1mg 基本售价：
2492.0 元 规格：
1 mg
产品信息
概述| 货号 | 21155-1mg |
| 描述 | TASIN-1 is a small molecule inhibitor that specifically kills cells with adenomatous polyposis coli (APC) truncations (IC50 = 70 nM) but spares cells with wild-type APC.1 TASIN-1 is effective in vivo, inhibiting tumor growth of colorectal cancer (CRC) cells with truncated APC, but not wild-type CRC cells, in a mouse xenograft model.1 TASIN-1 decreases cholesterol biosynthesis in APC-truncated cells but not in wild-type APCcells.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Zhang, L.,Theodoropoulos, P.C.,Eskiocak, U., et al. Selective targeting of mutant adenomatous polyposis coli (APC) in colorectal cancer. Sci. Transl. Med. 8(361), 361ra140 (2016).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 352.5 |
| 分子式 | C18H28N2O3S |
| CAS号 | 792927-06-1 |
| 稳定性 | ≥ 2 years |
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