(±)-SKF 81297 (hydrobromide)
货号：
15067-25mg 基本售价：
2492.0 元 规格：
25 mg
产品信息
概述| 货号 | 15067-25mg |
| 描述 | (±)-SKF 81297 is a selective agonist of the dopamine D1-like receptor (Ki = 1.9 nM).1 It demonstrates comparatively lower binding affinity for the dopamine D2, dopamine D3, serotonin 5-HT2A, and adrenergic α2 receptors (Kis = 1,272, >10,000, 955, and 509 nM, respectively).1 Activation of dopamine D1-like receptors by selective agonists such as (±)-SKF 81297 have been implicated in initiating a cascade of signaling events leading to reward-related incentive learning.2 |
| 别名 | (±)-6-chloro-PB; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Neumeyer, J.L.,Kula, N.S.,Bergman, J., et al. Receptor affinities of dopamine D1 receptor-selective novel phenylbenzazepines. European Journal of Pharmacology 474(2-3), 137-140 (2003).
2.Beninger, R.J. and Miller, R. Dopamine D1-like receptors and reward-related incentive learning. Neuroscience and Biobehavioral Reviews 22(2), 335-345 (1998).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 370.7 |
| 分子式 | C16H16ClNO2 • HBr |
| CAS号 | 67287-39-2 |
| 稳定性 | ≥ 2 years |
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