DAPT
货号:
1855-5 基本售价:
2475.0 元 规格:
5mg
产品信息
概述货号 | 1855-5 |
描述 | Cell permeable. A potent inhibitor of γ-secretase (IC₅₀ = 115 nM for total β-amyloid, IC₅₀ = 200 nM for β-amyloid 1-42). It reduces Aβ levels in vivo in plasma and cerebrospinal fluid in young and aged Tg2576 mice. Antagonizes Notch signaling through inhibition of Notch processing. DAPT treatment can influence hematopoietic cell fate decisions and enhances neuronal differentiation in embryonic stem cell-derived embryoid bodies independent of sonic hedgehog (shh) signaling. |
性能供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | -20℃ |
外观 | White to off-white solid |