| 货号 | 4421/1 |
| 供应商 | Tocris |
| 生物活性 | Peptide based on the lipopolysaccharide (LPS)-binding region of human lactoferricin. Neutralizes LPS; displays antimicrobial activity against Gram-negative and Gram-positive bacteria. Analog lauryl-LF 11 (Cat. No. 4422) available. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1529.81 |
| 分子式 | C69H112N26O1 |
| 可溶性/溶解性 | Soluble to 2 mg/ml in 20% acetonitrile / water |
| 序列号 | FQWQRNIRKVR (Modifications: Arg-11 = C-terminal amide) |
| 参考文献 | Sanchez-Gomezet al (2008) Comparative analysis of selected methods for the assessment of antimicrobial and membrane-permeabilizing activity: a case study for lactoferricin derived peptides. BMC Mirobiol. 11 196. PMID: 19014450. Andraet al (2005) Enhancement of endotoxin neutralization by coupling of a C12-alkyl chain to a lactoferricin-derived peptide. Biochem.J. 385 135. PMID: 15344905. Japeljet al (2005) Structural origin of endotoxin neutralization and antimicrobial activity of a lactoferrin-based peptide. J.Biol.Chem. 280 16955. PMID: 15687491. |