KL 001 (10 MG)
货号:
4685/10 基本售价:
2458.8 元 规格:
10 mg
产品信息
概述货号 | 4685/10 |
别名 | N-[3-(9H-Carbazol-9-yl)-2-hydroxypropyl]-N-(2-furanylmethyl)methanesulfonamide |
性能供应商 | Tocris |
生物活性 | Cryptochrome protein (CRY) stabilizer; blocks proteasome-mediated degradation of CRY1 and CRY2. Lengthens circadian period in mouse NIH-3T3 fibroblasts without altering casein kinase activity. Represses glucagon-induced hepatic gluconeogenesis through the induction of Pck1andG6pcexpression. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
纯度 | >98 % |
计算分子量 | 398.48 |
分子式 | C21H22N2O4 |
可溶性/溶解性 | Soluble to 100 mM in DMSO and to 20 mM in ethanol |
参考文献 | Hirotaet al (2012) Identification of small molecule activators of cryptochrome. Science 337 1094. PMID: 22798407. |